Search results for "Calcinosis cutis"
showing 2 items of 2 documents
Family studies in scleroderma (systemic sclerosis) demonstrating an HLA-linked increased chromosomal breakage rate in cultured lymphocytes
1988
An increased chromosomal breakage rate (ICBR) was found in 27 of 28 patients with scleroderma (systemic sclerosis, SS) - 5 with the syndrome including calcinosis cutis, Raynaud phenomenon, esophagus hypomotility, sclerodactyly and telangiectasia (CREST), 4 incomplete CREST, 1 overlapping syndrome, 18 progressive systemic sclerosis (PSS). Not only the patients, but also about half of their first-degree relatives showed an increased chromosomal breakage rate (more than 5 breaks per 100 metaphases). This character segregated as a dominant marker in nine families of scleroderma patients. In the six informative of the nine families, the ICBR trait showed close linkage with the HLA region on chro…
Calcinosis cutis metastásica
2012
Con el termino calcinosis cutis se engloban un conjunto de trastornos caracterizados por el deposito cutaneo de sales de calcio de forma primaria o secundaria. El diagnostico se confirma histopatologicamente. El pronostico suele ser benigno y el tratamiento debe ser individualizado. A continuacion, presentamos el caso de una paciente pluripatologica remitida al Servicio de Dermatologia por presentar placas subcutaneas bilaterales y simetricas en region pretibial.