Search results for "Calcinosis cutis"
showing 2 items of 2 documents
Calcinosis cutis metastásica
2012
Con el termino calcinosis cutis se engloban un conjunto de trastornos caracterizados por el deposito cutaneo de sales de calcio de forma primaria o secundaria. El diagnostico se confirma histopatologicamente. El pronostico suele ser benigno y el tratamiento debe ser individualizado. A continuacion, presentamos el caso de una paciente pluripatologica remitida al Servicio de Dermatologia por presentar placas subcutaneas bilaterales y simetricas en region pretibial.
Family studies in scleroderma (systemic sclerosis) demonstrating an HLA-linked increased chromosomal breakage rate in cultured lymphocytes
1988
An increased chromosomal breakage rate (ICBR) was found in 27 of 28 patients with scleroderma (systemic sclerosis, SS) - 5 with the syndrome including calcinosis cutis, Raynaud phenomenon, esophagus hypomotility, sclerodactyly and telangiectasia (CREST), 4 incomplete CREST, 1 overlapping syndrome, 18 progressive systemic sclerosis (PSS). Not only the patients, but also about half of their first-degree relatives showed an increased chromosomal breakage rate (more than 5 breaks per 100 metaphases). This character segregated as a dominant marker in nine families of scleroderma patients. In the six informative of the nine families, the ICBR trait showed close linkage with the HLA region on chro…